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Indeed, the mutation P478L of OCTN2, abolished only the carnitine transport activity (Seth et al., 1999)
The isoelectric point is 4.65.1 , making it acidic and negatively charged at physiological pH
Similar to ferroptosis, GPX4 has also been recognized as an antiapoptotic factor both in vitro and in vivo [85,86,87]
In our analysis, we found a novel BCAA fasting marker, ketovaline, in addition to isoleucine, keto(iso)leucine, leucine, and valine, which were previously known (Figs 3a and S2)
Most patients receive injections once or twice a week
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