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2 In the acute setting, discontinuation of the offending drug is necessary

More details for statistical tests are indicated in the legend of each figure

Retatrutide : Not yet submitted for regulatory approval

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Melanotan I Originally developed for medical purposes, such as treating rare light-sensitive conditions like erythropoietic protoporphyria (EPP), Melanotan I is approved in some contexts under strict medical supervision (e.g., Scenesse)