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Patients with elevated cardiac risk often experience measurable benefits
therefore, it is conceivable that the use of GLP-1RAs may be beneficial in these patients groupsalthough no studies have specifically assessed these mechanistic aspects in relation to psychopathology in humans thus far
The STEP UP trial evaluated a higher investigational dose of 7.2 mg and produced even more impressive outcomes: a mean weight loss of 21%, with over 90% of participants achieving at least 5% weight reduction and one-third losing 25% or more of their body weight
While short-term use under supervision may be tolerated, extended use could pose unknown risks
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