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SLC1A5 expression seems to be a prerequisite for the lineage commitment of both Th1 and Th17 cells (105), placing it high on the list of potential upstream regulators of the pathogenic differentiation of short-lived effector T cells encountered in RA patients ( Lipids as a Catalyst for Autoimmune Joint Inflammation Like glucose and amino acids, lipids are an essential nutrient resource for protective and pathogenic immune cells
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