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PMID 26579439
injections of 100 nmol kg 1 PYY analogue ( n = 7 mice and n = 6 cages), 100 nmol kg 1 PYYMK-801 ( n = 7 mice and n = 4 cages), 100 nmol kg 1 GLP-1MK-801 ( n = 7 mice and n = 5 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) for 6 days
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The team hopes to use newer techniques in future studies to track how GLP-1 drugs affect neurons over days or even weeks
Temperature and storage matter as much as timing: tirzepatide pens and vials must stay refrigerated between 36F and 46F until use, then reach room temperature (6877F) 1530 minutes before injection for comfortable administration
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