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That decision belongs to the prescriber, not to self-adjustment

While systemic injection also delivers peptides to the brain via blood circulation, nasal delivery may provide more direct CNS access for some portion of the dose

The honest answer: it depends on how much anti-inflammatory coverage your protocol needs

This transition usually coincides with the dose escalation past 7.5mg, when the injection volume from the lower concentration exceeds practical syringe limits

Key Takeaways Imcivree targets specific genetic obesity disorders like Bardet-Biedl syndrome and POMC/PCSK1/LEPR deficiencies, while Wegovy is used for general obesity treatment