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These results suggest that upon depletion of GSH, tissues undergo reprogramming to hyperactivate NRF2, possibly as a mechanism to upregulate adjacent antioxidant pathways and buffer oxidative stress induced upon GSH depletion
Type of study: non-rct experimental Number of citations: 44 Year: 2020 Authors: Hengke Guo, Siyu Guo, Hongmei Liu Journal: Bioorganic chemistry Journal ranking: Q1 Key takeaways: Se-rich yeast peptide fraction containing selenium and bioactive peptides shows the highest antioxidant activity and effectively reduces UVB radiation-induced skin damage
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Thats comparable to bariatric surgery
Further research on microbe-microbe and microbe-host associations may explain how specific metabolites affect the disease process
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