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Great so far, minimal side effects
Inflammasome involvement in PD pathogenesis has been investigated in both patients and animal models
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And the evidence base that will land in front of the committee is, on most of these compounds, thin
In summary, the key interactions to consider are pyridoxines reduction of levodopa and anticonvulsant efficacy, niacinamides additive effects on blood pressure, blood sugar, and gout management, and the potential need for B-vitamin repletion in patients on certain medications (diuretics, isoniazid, etc.)
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