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While the Fe-S cluster is critical for activity, its role for the reaction mechanism remains unclear ( in vitro using glutathione disulfide (GSSG) or in vivo in response to ozone and paraquat, and inactivated upon reduction ( Four APK proteins exist in Arabidopsis, APK1, 2, and 4 locate in plastids whereas APK3 is in the cytosol ( m value around 250 mV at pH 7) is consistent with the observed reduction by GSH
When to contact your provider: Redness that spreads beyond the injection area or worsens after 24 hours
doi: 10.1016/j.autrev.2014.11.012 112 GoodsonNMarksJLuntMSymmonsD
As such, there is no agreed recommended safe dosage, and some side effects might occur depending on individual response
Minor side effects are rare but can include nausea or mild irritation at the injection site
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