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Zolk et al., 2020)
Several epigenetic agents targeting these pathways have progressed into clinical development
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Bitter vegetables such as chicory, dandelion, radicchio, and artichoke contain sesquiterpene lactones that stimulate bile secretion and activate intestinal TAS2R bitter-taste receptors, generating a combined sensory and hormonal signal that triggers CCK release and colonic reflex activity ( Dietary fats, particularly those rich in monounsaturated and polyunsaturated fatty acids, such as EVOO, nuts, and avocado, further enhance CCK-mediated gallbladder contraction and bile secretion
Estudios cardiovasculares de resultados: Los ensayos LEADER (liraglutida), SUSTAIN-6 (semaglutida) y REWIND (dulaglutida) han proporcionado evidencia robusta de beneficios cardiovasculares en pacientes con diabetes tipo 2
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