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Long-term supplementation with LC is likely safe at doses of 2 g/day, but it may lead to indigestion, vomiting, diarrhoea, nausea, or fishy body odour at doses of 3 g/day (Rebouche, 1999)

Ingredient lists on these products tend to feature supplement style components: berberine is a common one, which is why berberine patches show up as their own category, alongside green tea extract, chromium, cinnamon, and B vitamins

In addition, there was no significant difference in the degree of neuronal loss between male and female GCLC-KO mouse (Fig

However, the available human research is limited, and controlled clinical trials have not demonstrated consistent or substantial benefits

Its widespread adoption owes to extensive scientific research validating its efficacy and safety, driving consumer trust and market demand