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To dissect the role of caspases in the observed profile, we included two inhibitors: Q-VD-OPh (referred to hereafter as QVD), a pan-caspase inhibitor targeting caspases 1, 3, 7, 8, 9, 10 and 12, and Ac-DEVD-CHO (referred to hereafter as DEVD), which selectively inhibits caspases 3, 6, 7, 8 and 10

Its multi-use vial format allows repeated access in controlled environments while maintaining product integrity

We still require controlled human trials, standardized dosing, and long-term safety studies

The preservative systems in compounded formulations are typically less robust than those in manufactured products, meaning room temperature exposure degrades the medication faster

Factors like insufficient sleep, prolonged screen exposure, and environmental stressors all play a role