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Guzman CB, Zhang XM, Liu R, Regev A, Shankar S, Garhyan P, et al
Blanpied TA, Scott DB, Ehlers MD (2002)
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Potential analytical variables include: Metal-binding affinity Stoichiometry Complex formation Free copper concentration Competition with other ligands Redox state Charge distribution Time-dependent dissociation A copper-binding observation does not establish delivery of copper to a specific tissue, cellular benefit, or therapeutic effect
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