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It binds to both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor, triggering cascading metabolic effects that influence appetite, insulin sensitivity, fat metabolism , and gastric emptying speed

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2g), which was associated with increased caspase-3 activation (Fig

In addition, people who have undergone gastrointestinal surgery may have a reduced ability to naturally absorb this vitamin from food

These setbacks demonstrate that while GLP-1 RAs show promising biomarker effects in the brain, translating them into meaningful clinical outcomes in neurodegeneration remains an unresolved challenge