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Acta Biochim Biophys Sin
Common signs include: Ongoing fatigue or weakness Pale skin Numbness or tingling in the hands and feet Brain fog, forgetfulness, or trouble concentrating Low mood, anxiety, or irritability Poor appetite or digestive upset When B12 is low, your metabolism slows, you have less energy for activity, and appetite signals can get thrown off, all of which make weight loss harder
World Health Organization (WHO)
And when leaky gut is present, a leaky blood-brain barrier can also be present
Sen, S., Kawahara, B., Gupta, D., Tsai, R., Khachatryan, M., Roy-Chowdhuri, S
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