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In our study, PFD did not inhibit fibrosis significantly, which was possibly due to the short duration of the medication (with normal dosing involving 6 weeks of administration in a mouse model and 3-6 months in clinical trials 19,42,43 )

The future of T1D research hinges on leveraging advanced human models, such as single-cell multiomics, patient-specific data, hPSC-derived cells, and organs-on-chips, to bridge the divide between foundational animal studies and clinical pathology

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