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Unpredictable side effects and safety While microdosing is used to reduce the risk of side effects, this is not supported by any clinical trials
Phase 2 reported -24.2% body weight at 48 weeks at 12 mg, and Phase 3 TRIUMPH-4 reported up to -28.7% at 68 weeks at 12 mg
The amount of protein was determined using BCA Protein Quantification Kit (Vazyme, E112-02)
Nat Rev Nephrol 12(6):325338 Miyazawa H, Hirai K, Ookawara S, Ishibashi K, Morishita Y (2017) Nano-sized carriers in gene therapy for renal fibrosis in vivo
Special considerations for lean individuals If you have lower body fat, the risk of accidental muscle injection increases significantly
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