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The mRNA expressions of aminopeptidase N ( APN ) and oligopeptide transporter ( PEPT1 ), which function in protein and amino acid digestion and absorption, and glutamate dehydrogenase 1a and 1b ( GDH1a, GDH1b ), which are essential in amino acid catabolism, were not affected significantly by dietary L-carnitine supplementation in the liver and muscle (Fig

The second is dose and route translation : even where an effect is real in a mouse, the human-equivalent dose is not a simple body-weight scaling, and as the route section above stressed there is no human bioavailability figure to anchor an oral-versus-injected comparison

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