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It works like a GLP-1 agonist, but also targets a hormone called glucose-dependent insulinotropic polypeptide (GIP) to help break down sugar and fat, according to Chatham

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A balanced reading of the literature is that ipamorelin and CJC-1295 reliably raise GH and IGF-1 in study settings, but the translation of those biomarker changes into durable, clinically meaningful outcomes in healthy adults remains insufficiently established

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When both systems are activated, some individuals experience stronger appetite reduction than expected, while others tolerate the combination without difficulty