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& Harris, J
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& Ravetch, J
cDNA microarray analysis of rat Achilles tendon fibroblasts identified the growth hormone receptor as one of the most abundantly up-regulated genes following exposure to the peptide, with concentration- and time-dependent increases confirmed at both mRNA and protein level, and downstream Janus kinase 2 activation observed on subsequent growth hormone stimulation [3]
Deficiency symptoms in children include developmental delay, regression, irritability, involuntary movements, and hypotonia
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