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The OASIS 4 trial showed 13.6% mean weight loss (16.6% with full adherence) at 64 weeks for oral semaglutide 25 mg
Although the mean estimated glomerular filtration rate (eGFR) remained above 60 mL/min/1.73 m 2 (with an average eGFR of approximately 73 mL/min/1.73 m 2 ), alanine transaminase (ALT) levels were mildly elevated, surpassing 30 IU/L (with an average ALT of approximately 33 IU/L) (Table 2)
This may make it more likely that acid will build up in the stomach
Answered any concerns I had, no matter how silly my question may have seemed to me, it was answered thoroughly and in a way which allowed me to understand
Following treatment, the medium was removed, cells were washed 2 times with warm PBS, and fixed with 4% formaldehyde for 20 min
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