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Clinical studies (in both obesity and type 2 diabetes) consistently show that GLP-1 RA treatment leads to less hunger, increased satiety, and spontaneous decreases in daily caloric consumption (Zheng et al., 2024)
Texture is a big one
In fact, proinflammatory cytokines are often released during the headache phase of a migraine by the major pain-signaling pathway in the brain, known as the trigeminovascular system
O'Brien S, Kantarjian H, Feldman E, Beran M, Andreeff A, Keating M, Koller C, Talpaz M
This finding was later combined with research by Joel Habener and jointly published in JCI
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