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The challenges faced by FOXO4-DRI are not unique in the realm of senolytic therapies

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B12 is water-soluble and generally safe to take with most supplements

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Microbiota-derived metabolites and gut hormone signaling SCFAs and GLP-1 crosstalk The gut microbiota and its derived metabolites play a central role in modulating host metabolism, immune function, insulin sensitivity, and overall health (57)

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