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mTORC1 beyond anabolic metabolism: regulation of cell death
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For example, clinical trials evaluating PDE1 and PDE10A inhibitors have yielded inconsistent outcomes, with some compounds showing improvements in cognitive or negative symptoms while others failed to achieve primary outcomes (Table 2)
For six months, nine months, a year, two years in some cases, depends how elevated the parietal cell antibodies are, but they do reliably start to lower with weekly injections
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