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First, as the water freezes and expands, it can create micro-fractures in the glass vial or compromise the seal of the rubber stopper, potentially allowing contaminants in upon thawing
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The problem comes when people start experimenting with these substances off label, without medical supervision, and in some cases without any clinical testing data at all to back them up
Research shows local cold application produces measurable reductions in inflammatory markers similar to whole-body approaches for localized injuries
Zhu M, Zhang QJ, Wang L, Li H, Liu ZP
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