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Know when to adjust

While clinical trials adhere to standardised titration protocols to evaluate efficacy, clinical practice allows for a slower, individualised approach, particularly for patients experiencing early GI symptoms

"Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis." Diabetes, Obesity and Metabolism, 2026;28(1):83-93

This divergence coincides with the CVS formulary change and is further reflected in first-time prescribing patterns

Last year, the Therapeutic Goods Administration approved the use of Ozempic to help reduce kidney disease progression in people with type 2 diabetes and chronic kidney disease