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Specifically, robust evidence from large-scale, multicenter randomized controlled trials is still needed to conclusively establish efficacy, determine optimal dosing and timing strategies, and fully evaluate safety before widespread clinical adoption in RDS management can be recommended

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14.4 Noncirrhotic Metabolic Dysfunction-associated Steatohepatitis with Moderate to Advanced Liver Fibrosis in Adults Treated with WEGOVY Injection Overview of Clinical Trial The efficacy of WEGOVY injection was evaluated based on an efficacy analysis at Week 72 in Study 11 (NCT#04822181), a 240-week, randomized, double-blind, placebo-controlled trial

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The manufacturer is now targeting markets where Novos main semaglutide patent is expiring next year, such as Canada and Brazil, to sell the ingredient to generic drugmakers, he said

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Randomized clinical trials remain the gold standard for evidence generation, but dedicated clinical trials for all comparisons are unlikely to materialize

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