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Regional Disciplinary Medical Board: vitamin B12 cannot be overdosed In 2009, the Regional Disciplinary Medical Board in Eindhoven stated very clearly that an overdose is not possible: There can be no question of an overdose of hydroxocobalamin, as the excess is excreted in urine by the kidneys and therefore cannot accumulate in the body
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In clinical trial protocols, retatrutide followed a structured dose-escalation schedule designed to minimise gastrointestinal side effects the most commonly reported adverse effects with this class of medication
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