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(PubMed) Jia K, Wang R, Tian J
These proliferative actions occur through activation of anabolic signaling pathways that coordinate increased DNA synthesis, enhanced protein production, and accelerated cell division across target tissues
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Specifically, the process comprises sequentially synthesizing racemic 4-chloro-3-hydroxybutyronitrile and racemic 4-chloro-3-hydroxy butyric acid alkyl ester under specific reaction conditions, using racemic epichlorohydrin as a starting material, preparing (R)-4-chloro-3-hydroxy butyric acid alkyl ester from stereoselective hydrolysis of the racemic 4-chloro-3-hydroxy butyric acid alkyl ester using an enzyme, and preparing L-carnitine or acetyl L-carnitine hydrochloride from the (R)-4-chloro-3-hydroxy butyric acid alkyl ester, according to the known method
2022, doi: 10.1016/j.cub.2022.07.020
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