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Characteristics unique to PWS, such as food-seeking behaviors and high threshold for pain, likely contribute to the risk for SA
Dysfunctional lysosomes release the ferroptosis drivers iron, Ca 2+ and cathepsin B (catB), promoting neuronal and oligodendrocyte loss, reflected in the white and gray matter pathology
As such, any patient on weight loss or drugs should be very conscious of what they eat and how much they exercise
Unfortunately, despite significant advances in anti-glycemic therapies, macrovascular complications are still the most common cause of death in T2D patients [5]
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