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Independent research groups outside the original Sikiric-Seiwerth laboratory have published on the musculoskeletal soft-tissue findings, providing cross-laboratory replication of the core repair-model claims (PMID 30915550)

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Mechanisms underlying neuroprotection include enhanced cerebral angiogenesis supporting tissue oxygenation, anti-inflammatory effects reducing secondary injury, antioxidant activity limiting free radical damage, and modulation of neurotransmitter systems including the dopamine/glutamate/NO system