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Despite binding to different receptors, their effects converge on protein kinases (PKA, PKB, PKC) and transcription factors like PPAR-gamma, a key regulator of lipid metabolism

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GLP-1 RA-Related Facial Aging The rapid and significant weight loss induced by GLP-1 RAs often leads to a noticeable reduction in facial fat pad volume, along with a decline in skin collagen, elastin, and essential nutrients

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