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Therefore, to further dissociate the effects of GSH and NRF2 on lipid abundance and assess if NRF2 activation alone mimics the effects of liver-specific Gclc deletion, we treated Gclc WT mice with CDDO-methyl (CDDO-Me), a form of bardoxolone with increased bioavailability

1998 Nov;28(11):1083-92

Activated CAFs facilitate tumor cell growth, invasiveness, and drug resistance by depositing extracellular matrix (ECM) and secreting cytokines, chemokines, and growth factors (zdemir et al., 2014)

The sample size was established based on comparable past research and established procedures in our laboratory

Ethics declarations Ethics approval and consent to participate The study protocol was conducted according to the guidelines contained within the Declaration of Helsinki and was approved by the ethics committees of Yokohama City University and Kyoto Prefectural University