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10.1677/joe.0.1040053 J
The removal happened because the original nominators voluntarily withdrew their nominations it is not an FDA determination that these compounds are safe or approved for compounding
Peer-reviewed studies demonstrate that GHK-Cu can: Stimulate fibroblast proliferation and collagen synthesis Increase glycosaminoglycan production Support wound contraction and remodeling Reduce oxidative stress and inflammation A major review published in the International Journal of Molecular Sciences describes GHK-Cu as a compound that resets gene expression to a healthier state, influencing over 4,000 human genes involved in tissue repair and anti-inflammatory processes
In 2015, a Cognitive Vitality Report released by the Alzheimers Drug Discovery Foundation stated that two multi-year treatment trials had found that epithalamin, from which epitalon is isolated, had imparted no severe adverse events in older adults, and that preclinical trials supported a favorable safety profile.35 Ten years later, a systematic review published in 2025 stated that information regarding critical issues about this peptides safety is missing.1 In terms of human trials, the best case we have in support of epitalons safety is a 2002 trial involving 162 patients in which no one in the epitalon group reported serious side effects.36 At the same time, the U.S
