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Plasma levels of hepatotoxic makers such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT), as well as albumin concentration, were comparable among tested groups, indicating no significant safety concerns, despite the higher occurrence of knockout over knock-in events (Fig

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Increased glycolytic enzyme pools in the cytoplasm allow for elevated glycolytic flux and glycolytic capacity, leading to faster ATP production and enhanced glucose-stimulated insulin secretion

Colleen Becker is a project manager in NCSLs Health Program.

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