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The capacity of GPX4 to influence cell viability through several pathways highlights its potential as a promising therapeutic target for malignancies

Seelig GF, Meister A (1984) -Glutamylcysteine synthetase

Data were fitted by one-phase decay, dotted lines represent 95% confidence interval (CI)

Moreover, DEX treatment (0.5 g/kg/h, pumping injection, before induction of anesthesia to the end of surgery) has been reported to reduce cardiac troponin I and MDA levels and to decrease the incidence of arrhythmias in patients undergoing cardiac valve replacement [234, 235]