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10.1200/jco.2015.63.3511 22 ChanM
Each therapeutic option was thoroughly explained, and patients were assigned to Groups A, B, or C based on several factors such as economic situation (e.g., TZP was not prescribed to those could not afford its costs), the desire to delay pharmacological treatment, and the presence of contraindications
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Further experiments show that pyridoxine supplementation increases the resistance of nigral dopaminergic neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity in wild-type mice as well as in astrocytic Drd2 conditional knockout mice
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