Many insurers are pulling coverage for GLP-1 drugs due to their high price, forcing patients to stop treatment even when it works
PMID: 25563749
So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets
(Oral semaglutide must be taken in the morning on an empty stomach.) Traditional oral GLP-1s, such as oral semaglutide, are broken down quickly in the stomach
270, R1148R1155.Google ScholarPubMed White, A, Louey, S, Chang, EI, et al