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Key mental health effects reported include: Increased anxiety and overwhelming feelings Episodes of depression Changes in emotional responses Mood fluctuations Difficulty managing daily stressors Healthcare providers emphasize that mental health side effects should not be overlooked
What to watch Trial design & endpoints: Will patient selection be broad or narrowly targeted (e.g., BMI, comorbidity)
Additional Phase 3 readouts in diabetes, cardiovascular disease, and several other indications are scheduled through 2026
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