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Activated microglia release chemokines, cytokines, and reactive oxygen species, crucially contributing to neuroinflammatory cascades while disrupting neurotransmitter balance and synaptic plasticity through pro-inflammatory phenotypic transformation

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Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE, EMPA-REG OUTCOME Investigators

doi: 10.1038/s41467-024-53006-w 46 MaoYShiDLiGJiangP