Major challenges in hydrogel-based delivery systems include difficulties with large-scale production, difficulties in precisely controlling gelation, the risk of immunogenicity, and the possibility of uneven drug distribution and retention within brain tissues
However, it is frustrating that no commercialized parasitic vaccine is available for humans, merely with several vaccines under different stages of clinical trials
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"Mechanisms of autoregulation of C3G, activator of the GTPase Rap1, and its catalytic deregulation in lymphomas." Sci