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Description

Glutamine is considered a nonessential amino acid due to endogenous synthesis

International Commission on Radiological Protection, ICRP

To enhance the cell permeability of RT, we converted the carboxylic acid groups to acetoxymethyl (AM) esters, which are readily hydrolysed by esterases to regenerate RT inside cells

10.3892/mmr.2018.9688 68 WrightE

Cellular and humoral immunity in the pathogenesis of AITD In addition to genetic, cellular and humoral immune mechanisms, loss of immune tolerance to thyroid autoantigens is the basis for the development of AITD