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Liraglutide (Saxenda) has a separate NICE appraisal (TA664) with more specific eligibility criteria: BMI 35 kg/m (or ethnicity-adjusted equivalent) with non-diabetic hyperglycaemia (pre-diabetes) and high cardiovascular risk Must be used within a specialist weight management service Similar ethnicity-adjusted BMI thresholds apply as for semaglutide A 12-week assessment at the 3 mg dose is recommended
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(f) Quantification of CD68 expressions in APP23/PS45 mouse brains, the number represents mean s.e.m., n = 30 mice total, A two-tailed students t -test was performed for statistical analysis
Typically once per day, but dosage can vary based on response and goals
