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doi.org/10.1056/NEJMoa2301972 Coskun, T., et al

Some animal studies have shown potential harm to the developing baby

The data is now telling us what clinical instinct always suggested that a lower individualised maintenance dose may be the sweet spot

However, while this initial hepatic fat accumulation represents a key early event, it is insufficient on its own to drive disease progression

[7] [9] Use is also contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency, as high doses of ascorbic acid may induce hemolysis in this population