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Dihexa (chemical name: N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a synthetic neuropeptide developed by researchers at Washington State University (WSU)
10.1038/s41569-018-0030-z Summary Keywords D-Gal, endothelial cell senescence, FOXO4-DRI, P53, ROS Citation Hu Z, Li F, Hu C, Shan Q, Tang Z, Jiang M, Yi X, Chen X, Jin L, Wang X and Wang Y (2026) FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway
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This will enable pooled analyses and accelerate learning
Besides, AC591, as a standardized extract of HGWD, effectively alleviated cold hyperalgesia, mechanical allodynia, and morphological damage of DRG in OXA-treated rats ( Active ingredients of traditional medicine, such as curcumin (CUR), AC591, rosmarinic acid, quercetin, and rutin have also been studied for the prevention and treatment of PIPN
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