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Participants in the phase 2 trial lost an average of 7 kg (15 lbs) after 16 weeks, significantly more than the placebo group
The drug can also cause hypotension in some patients through effects on the autonomic nervous system, which can mean dizziness, fainting, or falls, particularly in older adults
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Similarly, as a result of the positive findings from the recent DAPA-CKD trial [90], dapagliflozin is now indicated for the treatment of CKD, and can be initiated if eGFR 25 ml/min/1.73 m 2
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