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Finally, acetyl-proteomics data in CrAT KO skeletal muscle showed that this perturbation increases mitochondrial acetylation, supporting the idea that CrAT can act as a buffer system for mitochondria acetyl-CoA, but also observed decreases in cytosolic protein acetylation 33
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A: Some people track changes within days to a few weeks, but responses vary
The challenge, as we will see in the clinical evidence section, is translating that theoretical appeal into measurable real-world results at a magnitude that matters
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