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Glutathione is more effective for pigmentation and brightening, while collagen targets firmness and wrinkles

Access this article Similar content being viewed by others Abbreviations -GCL: -glutamate cysteine ligase GGT: -glutamyl transferase BSO: L-buthionine-(S, R)-sulfoximine GPx: glutathione peroxidase GSH and GSSG: reduced and oxidized glutathione, respectively MAPK: mitogen-activated protein kinase miR: microRNA Nrf2: NF-E2-related factor 2 ROS: reactive oxygen species REFERENCES Scir, A., Cianfruglia, L., Minnelli, C., Bartolini, D., Torquato, P., Principato, G., Galli, F., and Armeni, T

If irritation occurs, discontinue use

This maintenance phase begins only after the initial deficiency has been corrected and the patients blood markers have stabilized within the normal range

Optineurin suppresses mtROS-regulated NLRP3 inflammasome activation by upregulating mitophagy in HG treated TECs (151)