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Specifically, the drug effectively inhibits the activation of the NF-B signaling pathway, leading to significant reduction in the mRNA expression levels of pro-inflammatory cytokines such as TNF-, IL-6, and IL-1, ultimately delaying the progression of muscle atrophy [29]
Supplementary Table 3) was rated as high for liraglutide, naltrexone plus bupropion, semaglutide and tirzepatide (Supplementary Table 6)
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