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Efficacy and safety of dulaglutide versus sitagliptin after 52 weeks in type 2 diabetes in a randomized controlled trial (AWARD-5)

Weekly injections that create a long, steady feeling of appetite control will feel different at the grocery store than a daily dose that causes sharper ups and downs in hunger

[1] The most frequently reported adverse effects in clinical trials were gastrointestinal in nature, including nausea (12-22%), diarrhea (12-16%), vomiting (6-10%), and constipation (6-7%), with rates varying by dose

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Since these areas lie at the interface between the brain and the body, drugs administered outside the brain can still influence neural activity there